Sphingobacterium multivorum has been reported as a rare microorganism causes diseases in patients with predisposing conditions. We describe the first case of invasive disease caused by S.multivorum in a patient without an underlying disorder. A 73-day-old boy with a fever to 39ºC, lethargy, vomiting, hypotonia and convulsion was admitted to Kocaeli University Faculty of Medicine Hospital on November 21st, 1999. The 15-year-old mother and baby were living in a tent-city in Izmit where an earthquake of 7.4 Richter scale centered on August 17th, 1999. S.multivorum was isolated from blood cultures. The infant received a 10-day course of ampicillin and cefotaxime and was discharged with and uneventful recovery. Both mother and patient were seronegative for HIV. At follow-up studies eight month later immune profile was normal. The evidence in the present case suggests that under certain circumstances S.multivorum may cause invasive disease in an otherwise normal host.