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2008, Cilt 38, Sayı 3-4, Sayfa(lar) 137-142
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Prevalence of antibodies against rubella, CMV and HSV among children in eastern Turkey
Muhammet Güzel Kurtoğlu1, Hamza Bozkurt2, Recep Keşli3, Oğuz Tuncer4, Mustafa Berktaş2
1 Van Education and Research Hospital, Microbiology and Clinical Microbiology Laboratory, Van
2 University of Yüzüncü Yıl Faculty of Medicine Depts. of Microbiology and Clinical Microbiology, Van
3 Maternal and Children Hospital, Microbiology Laboratory, Konya
4 University of Yüzüncü Yıl Faculty of Medicine Depts. of Pediatrics, Van
Keywords: Seroprevalence, Rubella, Cytomegalovirus, CMV, Herpes Simplex Virus, HSV

Viral infections can lead to a broad range of cutaneous and systemic manifestations in childhood. Infections may occur inutero, perinatal, postnatal or childhood. The purpose of this study is to determine the IgM and IgG antibodies seroprevalences of rubella virus, cytomegalovirus (CMV) and herpes simplex virus (HSV) in serum samples of pediatric patients, which were sent to our microbiology laboratory and to evaluate the results according to their age groups. A total number of 327 serum samples obtained from the pediatric patients between January 2003 and December 2003 were studied. The antibody levels of rubella IgM - IgG, CMV IgM - IgG and HSV type 1+2 IgM - IgG were detected using TKA 4HD micro-ELISA instrument and kits. IgM seropositivity for rubella, CMV and HSV type 1+2 were found as 3.4% (7/207), 4.3% (8/184), 10.2% (18/177) and the IgG seropositivity rates were 52.6% (131/249), 75.3% (134/178), 10.2% (16/157), respectively. Our results were compatible with the results obtained in other studies and it is an important finding demonstrating the confrontation of children with these viruses in Eastern region of Turkey.

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