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2009, Cilt 39, Sayı 1-2, Sayfa(lar) 048-051
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IS HEPATITIS E VIRUS TRANSMITTED THROUGH BLOOD TRANSFUSION?
Sinem AKÇALI1, Ömer AKÇALI2, Tamer ŞANLIDAĞ1, Serdar SÖYLEV2
1Celal Bayar Üniversitesi Tıp Fakültesi Mikrobiyoloji ve Klinik Mikrobiyoloji AD, Manisa
2Dokuz Eylül Üniversitesi Tıp Fakültesi Ortopedi ve Travmatoloji AD, İzmir
Keywords: Hepatitis E virus, transfusion, parenteral, transmission

Over recent years the main transmission route of hepatitis E virus (HEV) has been through faecal-oral transmission; however some studies stressed the parenteral transmission of HEV. Th e aim of this study was to evaluate of whether HEV can be transmitted to patients through blood transmission who are undergoing major orthopaedic surgery. 55 elective orthopaedic surgery patients who required blood transfusions and their 101 blood donors were included in the study. Th e patient sera were tested for HBsAg, anti-HCV, anti-HEV IgG and anti-HEV IgM preoperatively by micro EIA method. Th e blood donors which were negative HBsAg and anti-HCV, were investigated for anti-HEV IgG and anti-HEV IgM. Both serologic tests were performed for the patient blood samples 1 month aft er the operation. HBsAg and anti-HCV were negative in all patients both preoperatively and postoperatively. Anti-HEV IgG and IgM were positive in 9 and 2 blood donor samples, respectively. In patients sera, anti-HEV IgG were positive in 5 patients preoperatively and postoperatively. However, anti-HEV IgM was found negative in all patients. As a result, even though two donors had acute HEV infection, blood transfusion hepatitis did not develop in patients. It is concluded that, there is minimal risk of HEV infection through blood transfusion.

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