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2011, Cilt 41, Sayı 1, Sayfa(lar) 018-021
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Rate of Cephalosporin Resistance in Gram-Negative Bacteria Isolated from Hospital Sewage Contaminated Seawater
Tamer AKKAN1, Ayşenur KAYA2, Sadık DİNÇER3
1Giresun Üniversitesi Fen-Edebiyat Fakültesi Biyoloji Bölümü, Giresun
2Kilis Yedi Aralık Üniversitesi Fen-Edebiyat Fakültesi Moleküler Biyoloji ve Genetik Bölümü, Kilis
3Çukurova Üniversitesi Fen-Edebiyat Fakültesi Biyoloji Bölümü, Adana
Keywords: Gram-negative bacteria, antibiotic resistance, water pollution

Objective: In this study, rates of resistance of gram-negative bacteria isolated from sea water contaminated with hospital waste waters to cephalosporins frequently used in the treatment of gram-negative bacterial infections, were investigated.

Materials and Methods: A total of 85 gram- negative bacteria were isolated and identified with VITEK II Compact System and examined for cephalosporin resistance.

Results: The rates of resistance to cephazoline, cefuroxime, cefotaxime and cefepime were 85%, 28%, 8% and 5%, respectively. In addition, multidrug resistance index values of 81% of the isolates were higher than the reference value of 0.2.

Conclusion: The results of this study have indicated that an important proportion of gram-negative bacteria isolated from sea water contaminated with hospital waste discharge was resistant to cephalosporins and this situation carries a potential risk for public health.


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