Acute bacterial meningitis is a serious infectious disease characterized by high mortality. Various infectious agents can cause acute bacterial meningitis. Despite the reduced fatality rates due to rapid diagnosis and prompt treatment, mortality can still occur. This report presents a Strepto-coccus pneumoniae meningitis case identified by postmortem investigations. Post-mortem microbiological sampling can help us to obtain data about the etiology of fatal pneumoniae and provide evidence that will influence the treatment guidelines.