2005, Cilt 35, Sayı 2, Sayfa(lar) 119-122 |
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Hepatititis C Virus Seroprevalence and Risk Factors in Haemodialysis Patients |
Tamer Şanlıdağ1, Sinem Akçalı1, Dilek Ergin2, Adalet Koca Kutlu2 |
1Celal Bayar Üniversitesi Tıp Fakültesi Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Manisa 2Celal Bayar Üniversitesi Manisa Sağlık Yüksekokulu, Manisa |
Keywords: Haemodialysis, HCV, prevalence, risk factors |
The aim of this study was to determine the seroprevalence and risk factors of hepatitis C virus infection in different three hemodialysis units in Manisa . The study was carried out on 142 patients. Data collected through a interview administered questionnaire. The questions probes an age, gender, marital status, profession, training, blood transfusion, surgical procedure as independent variable. Blood samples taken from the patients were examined in Celal Bayar University, Medical Faculty, Microbiyology and Clinical Microbiyology Department. The sera were tested for antibodies against HCV by third-generation enzyme-linked immunosorbent assay (ELISA) (UBI HCV EIA, United Biologicals, Inc.) and genotyping of HCV . The data were analysed by SPSS 10.0 for Windows program software packet, χ2 and t-tests were used. The mean age of the subjects which composed of 52.8% male is 51.94±13.9. HCV seroprevelance was found as 21.7%. It was determined that %35.2 of the patients have blood transfusion story and 23.9 % of them have surgical procedures. The time period of hemodialysis was 55.83± 6.94 . The results of this study showed that, the transfusion story and surgical procedure have no significant statistical relationship which are both the risk factors of HCV infection while the relationship between the time period of hemodialysis and HCV infection are significant statistically.
In conclusion; HCV transmission in patients on haemodialysis is currently not related to blood transfusion or surgical procedures and suggest that nosocomial transmission within the haemodialysis unit plays a key role in HCV infection.
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