2017, Cilt 47, Sayı 1, Sayfa(lar) 033-038 |
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Bacterial Agents in Diabetic Foot Infections and Their Biofilm Formation Rates |
Ş. Barçın ÖZTÜRK, M. Bülent ERTUĞRUL, Esra ÇÖREKLİ |
Adnan Menderes Üniversitesi Uygulama ve Araştırma Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Aydın |
Keywords: Biofilm, diabetic foot, chronic wound |
Objective: The wound bed is an ideal surface for bacterial
growth, and the deleterious effects of microbial infection
on wound healing are recognized. Bacteria adhere to
almost all types of surfaces, and form complex structures
called biofilms. The aim of our study was to determine the
bacteria and biofilm formation rates in diabetic foot.
Material and Method: Routine culture samples obtained from
infected diabetic ulcers were evaluated in Infection Diseases
and Clinical Microbiology laboratory between 2013-2015. We
collected specimens for culture by debridement of the soft
tissue and / or bone biopsy and effective bacterial agents were
identified by using standard culture, and identification
methods. The production of biofilm was studied by quantitative
microdilution plate method.
Results: We isolated a total of 81 causative bacteria from
soft and/or bone tissue samples in 55 patients. The most
frequently isolated species was Pseudomonas (n=16;
19.8%). Sixty seven (82.7%) of 81 isolates produced
biofilm. We found that biofilm was produced by many types
of organisms, but it was particularly more common in
Staphylococcus and Pseudomonas species.
Conclusion: We believe that our work is important in that
it emphasizes the need to develop therapeutic strategies to
eliminate and/or prevent biofilm formation in diabetic foot
infection.
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