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2019, Cilt 49, Sayı 2, Sayfa(lar) 055-060
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An Innovative Molecule to Combat Infectious Agents: Squalamine
Emine Merve Alan, Mehmet Erman Or, Banu Dokuzeylül
İstanbul Üni̇versi̇tesi̇ Cerrahpaşa Veteri̇ner Fakültesi̇, İç Hastalıkları Anabi̇li̇m Dalı, İstanbul, Türkiye
Keywords: Squalamine, aminosterol, veterinary medicine

Antibiotic resistance, an important threat to human and animal health, is becoming a greater problem for the world every day. In particular, the increase in unconscious and uncontrolled use of antibiotics has complicated the management of antimicrobial therapy. For this reason, the interest in the antimicrobial effects of the aminosterol derivatives, a group of innovative molecules has increased in recent years.

In this review, it is aimed to provide detailed information about squalamine, which has been the subject of various studies due to its antibacterial, antiviral, antiparasitic and antifungal activities and we believe that it may provide a new therapeutic approach for combating viral infectious agents in veterinary field.


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