Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Telif Hakkı Devir Formu | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim  
2020, Cilt 50, Sayı 1, Sayfa(lar) 035-043
[ Türkçe Özet ] [ PDF ] [ Benzer Makaleler ]
Retrospective Evaluation of Toxoplasma gondii, Rubella and Cytomegalovirus Seropositivity and Avidity Test Results in Patients Admitted to İU-C Cerrahpaşa Medical Faculty Hospital Between 2013-2018
Esra Demir1, Harika Öykü Dinç2, Doğukan Özbey1, Seher Akkuş1, Sevgi Ergin1, Bekir Sami Kocazeybek1
1İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, İstanbul
2İstanbul Okan Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, İstanbul
Keywords: Toxoplasmosis, cytomegalovirus infections, rubella, IgG avidity

Objective: The aim of this study was to evaluate retrospectively results of the IgM and IgG antibody seropositivity and IgG avidity tests performed in serum samples obtained from patients with suspected Toxoplasma gondii, rubella and Cytomegalovirus (CMV) infections or for routine control for pregnancy follow up which were sent to Medical Microbiology Serology/ELISA Laboratory of Cerrahpaşa Faculty of Medicine between January 2013 and December 2018 with various clinical indications.

Method: T. gondii, rubella and CMV IgM antibodies examined by immunocapture ELISA method and T. gondii, rubella and CMV IgG antibodies detected by indirect ELISA method in serum samples of 84,807 patients who applied to Laboratories of Istanbul University Cerrahpaşa Faculty of Medicine Hospital between 2013-2018 were evaluated. In addition, IgG avidity test results were examined in serum samples of T. gondii, rubella and CMV IgG avidity tests were performed using indirect ELISA tests realized in 916 cases.

Results: In the study, IgM / IgG positivities for T. gondii, rubella and CMV were found to be 2.2% / 97.8%, 0.24% / 99.7% and 3.1%/ 94%, respectively. Avidity index tests for all three agents were requested for 274 (30%) cases with both IgM and IgG- positivities The detection rate of low avidity indices for T. gondii, rubella and CMV were 44 (16%), 9 (3.2%) and 8 (2.9%) respectively.

Conclusion: Multiple molecular tests provide a better understanding of the role of viral agents in respiratory infections in adults. We think that the detection of the viral agent with the diagnosis of the agent targeted in these infections will be beneficial in preventing unnecessary use of antibiotics with the correct treatment application and will provide fast and accurate management decisions for infection control measures.


[ Türkçe Özet ] [ PDF ] [ Benzer Makaleler ]
Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Telif Hakkı Devir Formu | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim