Objective: Toxoplasma gondii, rubella virus and cytomegalovirus (CMV) are important infectious agents that can be transmitted vertically from mother to baby, and can cause clinical signs in the fetus and the newborn. In our study, it was aimed to determine the distribution of antibodies against T. gondii, Rubella and CMV in pregnant women applied to our hospital.

Method: In our study, the serological test results of the blood samples of pregnant women used in the diagnosis of T. gondii, Rubella and CMV infections in Microbiology Laboratory of Sivas Cumhuriyet University Faculty of Medicine, were retrospectively analyzed in a two-year period between 2018 and 2019.

Results: The positivity rates were determined to be 26.7% for T. gondii IgG, 87.9% for Rubella virus IgG and 99% for CMV IgG. While IgM test positivities for the same pathogens were 1.3%, 0.3%, and 0.7%, respectively. Low avidity results were encountered in 4 patients (22.2%) for T. gondii, whereas the results of all examined tests for Rubella and CMV were found to have high avidity.

Conclusion: Regional epidemiological data are important to determine routine screening approach or infectious agents that will be more important for the newborn. We think that we will contribute to the literature with our study based on regional data.