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2022, Cilt 52, Sayı 4, Sayfa(lar) 291-298
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The Importance of SARS CoV 2 RT-PCR Positivity and Hematologic Parameters in COVID-19 Patients
Altan Akıneden1, Cemal Çiçek2, Selçuk Türkel2, Sibel Çiğdem Tuncer3
1Aksaray Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Aksaray, Türkiye
2Aksaray Üniversitesi, Tıp Fakültesi, Eğitim ve Araştırma Hastanesi, Tıbbi Mikrobiyoloji Laboratuvarı, Aksaray, Türkiye 3
Aksaray Üniversitesi, Tıp Fakültesi, Tıbbi Biyokimya Anabilim Dalı, Aksaray, Türkiye
Keywords: COVID-19, RT-PCR, Ct value, hematologic parametres

Objective: Diagnosis of COVID-19, the cause of the pandemic, relies on clinical, laboratory and radiological methods. In our study, the relationship between real-time PCR (RT-PCR) threshold cycle (Ct) value and hemogram sub-parameters was investigated in patients hospitalized in ward or intensive care unit with the diagnosis of COVID-19.

Methods: In our study, 98 cases hospitalized in the COVID-19 unit between November 2020 and January 2021 were investigated. According to the location, the cases were hospitalized either in the intensive care or in the ward. Age, gender, RT-PCR Ct values and hematological parameters of the patients were evaluated.

Results: Of the investigated cases, 45 were female and 53 were male. The mean age was 61.8 in the ward and 75.5 in the intensive care unit (p=0.02). No difference was observed between intensive care and ward patients for their RT-PCR Ct values (p=0.068). No difference was also found between leukocyte, neutrophil, thrombocyte, plateletcrit and platelet/lymphocyte ratio values (p>0.05) between the groups. However, lymphocyte, eosinophil, erythrocyte, hemoglobin values were decreased in intensive care patients compared to ward patients. On the other hand, erythrocyte distribution width-coefficient of variation, erythrocyte distribution width-standard deviation, platelet, mean platelet volume, platelet distribution width and neutrophil/lymphocyte ratio value were increased.

Conclusion: It was concluded that RT-PCR Ct values were not significant in terms of hospitalization in the ward or intensive care unit, but the follow-up of hematological parameters was important.


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