Objective: In this study, it was aimed to retrospectively evaluate the aerobic bacteria isolated from wound samples sent to the microbiology laboratory of our hospital and to determine their antibiotic resistance profiles.

Methods: Bacteria isolated from wound samples and received from different clinics to our laboratory between January 2018 and December 2021 were identified by conventional methods and automated identification system. Antimicrobial susceptibilities were determined using an automated system according to European Committee on Antimicrobial Susceptibility Testing (EUCAST, v 12.0) recommendations.

Results: A total of 1839 agents were isolated from 2502 samples in our study; among them, 912 (49.6%) were gram-negative, and 927 (50.4%) were gram-positive bacteria. The isolated bacteria were determined respectively as Escherichia coli (17.6%), coagulase-negative staphylococci (CoNS) (16.9%), Staphylococcus aureus (15.4%) and Pseudomonas spp. (10.1%). While vancomycin, teicoplanin and linezolid resistance were not found in staphylococci, methicillin resistance rates were %23.7 in S. aureus and %81 in CoNS. ESBL positivity was detected %55 of E. coli strains and %47 of Klebsiella spp. strains. It has been observed that the resistance rates of aminoglycoside and carbapenem group antibiotics were low in bacteria in the Enterobacterales order. In addition, it was determined that Acinetobacter spp. and Pseudomonas spp strains had the lowest resistance rates against amikacin.

Conclusion: In wound infections, regular determination of the infectious agents and their antimicrobial resistance profiles will contribute to reducing resistance rates by guiding empirical treatment and guiding judicious antibiotic use.