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2003, Cilt 33, Sayı 4, Sayfa(lar) 323-328
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Virulence Factors and Susceptibility Patterns of Candida Strains Isolated from Patients with Vulvovaginal Candidiasis
Ayşe Kalkancı1, Semra Kuştimur1, Gülendam Bozdayı1, Aydan Biri2
1Gazi University Faculty of Medicine, Department of Microbiology, Ankara
2Gazi University Faculty of Medicine, Department of Gynecology and Obstetrics, Ankara
Keywords: Candida, virulence factors, adhesion, proteinase, phospholipase, antifungal susceptibility
Abstract
Candida strains have different virulence factors to colonize vagina and to remain permanent there. The most important factors are the ability to adhere to epithelial cells and to produce the extracellular enzymes such as proteinases and phospholipases. In this study, we investigated the adherence ability, enzyme productions and the susceptibility patterns of the Candida strains. It was shown that the majority of Candida albicans strains were enzyme producers and were also adhesive to vaginal epithelial cells.
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