2009, Cilt 39, Sayı 3-4, Sayfa(lar) 062-068 |
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COMPARISON OF CERTAIN VIRULENCE FACTORS IN CANDIDA ALBICANS AND NON-ALBICANS CANDIDA STRAINS ISOLATED AS INFECTIOUS AGENT |
Mevlüt YILDIRIM, İpek MUMCUOĞLU, Şenol KURŞUN, Kamer KOLDAŞ, Vedat YETENER, Neriman BALABAN |
Ankara Numune Eğitim ve Araştırma Hastanesi II. Mikrobiyoloji ve Klinik Mikrobiyoloji Bölümü, Ankara |
Keywords: Candida albicans, non-albicans, virulence factors |
In this study fosfolipase, esterase, haemolytic activity and slime production in 92 Candida albicans and 40 non-albicans strains
which isolated from hospitalized patient was evaluated. Candida strains that isolated from oral cavity of healthy subjects was
used as a control group. Yolk egg agar method was used for detection of fosfolipase activity, Tween 80 agar method was used
for detection of esterase activity, 5% sheep blood SDA was used for detection of haemolytic activity and Congo red brain heart
infusion agar method was used for detection of slime factor. Fosfolipase, esterase, β haemolytic activity and slime production
was detected 91%, 84%, 87% and 17% in C.albicans strains and 73%, 35%, 70% and 33% in non-albicans strains respectively.
Fosfolipase and β haemolytic activity were significantly higher in C.albicans and non-albicans strains from patient group than
control group (p<0.05).
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