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2011, Cilt 41, Sayı 3, Sayfa(lar) 116-119 |
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The Distribution of the Genetic Subtypes of HIV-1 |
Tülay YALÇINKAYA1, Şükran KÖSE2 |
1Refik Saydam Hıfzıssıhha Merkezi Başkanlığı Salgın Hastalıklar Araştırma Müdürlüğü Viroloji Laboratuvar Şefliği AIDS Doğrulama Merkezi 2Tepecik Tepecik Eğitim ve Araştırma Hastanesi Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği |
Keywords: HIV-1, subtype |
Objective: The aim of this study was to assess the subtypes of HIV-1 strains isolated from HIV/AIDS patients.
Materials and Methods: A total of 34 plasma samples were studied (24 males, 10 females; mean age 36.7 years). First 1056 bases of the pol gene were directly sequenced from plasma of these 34 individuals and the sequences were used for genotypic analyses. Results: The majority of the HIV-1 isolates were found to be subtype B virus (61.8%). Subtypes A1 (14.7%), C (11.8%), G (8.8%), and CRF02_AG (2.9%) were also determined. Although HIV-1 subtype B is the dominant one, other subtypes were also identified. Conclusion: Our findings in the study and the bridging structure of the geographic localization of Turkey indicated the need for the national surveillance of the subtypes of HIV. |
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