Lyme disease is a multisystemic zoonosis caused by Borrelia burgdorferi. B. burgdorferi is a motile spirochete with loose spirals from Spirochaetaceae family and Lyme disease is acquired by humans through the bite of hard ticks of Ixodes species. Erythema migrans, acrodermatitis chronica atrophicans and morphea-like lesions present as skin lesions. Acrodermatitis chronica atrophicans that is the late lesion of Lyme disease and that is often seen in women over the age of forty presents as hyperemia and swelling and can lead to atrophy and sclerosis within months or years. In this study we report a case of acrodermatitis chronica atrophicans caused by B. burgdorferi infection.