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2017, Cilt 47, Sayı 1, Sayfa(lar) 026-032 |
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Antibacterial Activities of Extracts of Lichen Samples Collected from Balikesir Region on Escherichia coli ATCC 25922 |
Ezgi UÇARKUŞ1, Barış GÖKALSIN1, Nazlıhan YILDIRIM1, Birkan AÇIKGÖZ1, Gülşah ÖZYİĞİTOĞLU2, N. Cenk SESAL2 |
1Marmara Üniversitesi Fen Bilimleri Enstitüsü, Biyoloji Bölümü, İstanbul 2Marmara Üniversitesi Fen Edebiyat Fakültesi, Biyoloji Bölümü, İstanbul |
Keywords: Antibacterial activity, Escherichia coli, Parmelia saxatilis, Parmelia sulcata |
Objective: In this study, it was aimed to determine the
antibacterial activity of acetone extracts of Parmelia
saxatilis (L.) Ach. and Parmelia sulcata Taylor lichen
species that were collected from Balıkesir district, on the
strain of Escherichia coli ATCC 25922.
Material and Methods: After lichen samples collected from Balıkesir province were identified, the acetone extracts were obtained. Antibacterial and minimum inhibitory concentration (MIC) tests of the acetone extracts of lichens on Escherichia coli were performed via microdilution method. The antibiotic kanamycin was used as control group and a MIC value of the antibiotic was determined for comparison of antibacterial activities of the lichen acetone extracts. Results: Lichen acetone extracts and kanamycin dosages ranging between 2.5-40 μg/ml were tested. Kanamycin showed antibacterial activity at only concentration of 40 μg/ml and its MIC value was determined as 40 μg/ml. MIC values were also defined for the acetone extract of Parmelia saxatilis (20 μg/ml), and Parmelia sulcata (40 μg/ml). Conclusion: The acetone extract of Parmelia saxatilis had antibacterial effect on Escherichia coli much lower than that of kanamycin. The acetone extract of Parmelia sulcata also showed antibacterial activity that equals to those of kanamycin. According to the results that were obtained from this study, it has been predicted that lichen extracts that have higher antibacterial potential may be useful for treatment of bacterial infections in case essential tests are performed. |
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