Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Telif Hakkı Devir Formu | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim  
2018, Cilt 48, Sayı 1, Sayfa(lar) 001-013
[ Türkçe Özet ] [ PDF ] [ Benzer Makaleler ]
Bacterial Biofilms: Detection Methods and Role in Antibiotic Resistance
Aybala TEMEL, Bayrı ERAÇ
Ege Üniversitesi Eczacılık Fakültesi, Farmasötik Mikrobiyoloji Anabilim Dalı, İzmir
Keywords: Biofilm, biofilm detection, antibiotic resistance

Biofilms are micro-ecosystems that can occur on medical devices and biomaterials, or on host epithelial cells and mucosal surfaces, and play a role in many different diseases.

Methods for determining the formation of biofilm are very important for preventing biofilm infections. Since colorimetric methods which are frequently used to detect biofilm formation have various disadvantages, there is a need for standard, rapid and reliable methods. Various new technologies have been developed that can also be used for biofilm detection. Among these; “real-time cell analysis” method that detects the change in resistance to electric current, “fiber-optic sensor” method in which the change in penetration of infrared rays is measured, and “luminescent conjugated oligothiophene” method based on detecting biofilm matrix components are promising. With these methods, the structure of biofilm can be determined more sensitively, quickly and quantitatively.

In addition to the antibiotic resistance of planktonic bacteria, resistance that results from the biofilm structure, further complicates treatment of biofilm infections. It is thought that the biofilm resistance is a multifactorial event and multiple mechanisms occur simultaneously. In this review, the formation of bacterial biofilms and factors affecting them, biofilm detection methods, biofilm infections and factors that play a role in biofilm resistance are examined.


[ Türkçe Özet ] [ PDF ] [ Benzer Makaleler ]
Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Telif Hakkı Devir Formu | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim