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2023, Cilt 53, Sayı 1, Sayfa(lar) 001-009
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Bacterial Circadian Rhythm
Ayşegül Ateş, Şafak Ermertcan
Ege Üniversitesi, Eczacılık Fakültesi, Farmasötik Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye
Keywords: Circadian rhythm, cyanobacteria, oscillator

Circadian rhythm, which can also be defined as a molecular clock, is the whole of metabolic, biochemical, and hormonal changes. Circadian rhythm can be seen through molecular mechanisms with similarities and differences in prokaryotes, fungi, plants, and insects. These rhythm is also seen in cyanobacteria, which are thought to have an extremely simple lifestyle. Depending on the rhythm, it performs photosynthesis in day and nitrogen fixation at night. The circadian rhythm created by cyanobacteria has started to appear independent of the change in daylight after. This mechanism can be examined in three basic steps; ‘oscillator’, ‘input pathway’, and ‘output pathway’. The information coming to the oscillators from the input pathways is translated into gene expression, and by the output pathways, certain cellular activities occur in a daily rhythm. Rhythms that resemble the circadian rhythm are also observed in non-photosynthetic microorganisms. By considering the bacterial circadian rhythm, problems such as antibiotic resistance and dysbiosis can be combated in the field of medicine. In the field of industry and agriculture, innovations that can positively shape the quality of both the product and the production, can be realized.

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