Determination of anaerobic bacteria as infectious agents depends on the isolation and identification of the agent from the appropriate material. These processes are difficult, time-consuming and require experienced personnel. Following this, the fact that the antibiotic susceptibility tests of the isolated and identified bacteria are not performed in many medical microbiology laboratories or take a long time leads clinicians to empirical treatment options in the treatment approach. In addition, the differences in the methods routinely applied for all these processes cause us to encounter highly variable results in the data presented globally. The selection of antibiotics for empirical treatment in cases where anaerobic bacteria are considered to be the etiology is based on regional surveillance data. Therefore, it is important to present antibiotic susceptibility results periodically. In this review; In addition to providing information about antibiotic susceptibility test methods in anaerobic bacteria, it is aimed to present the periodic and regional similarities and differences in antimicrobial susceptibility test results by examining the data obtained on the subject at different time intervals in our country and in the world.