Objective: This retrospective study aimed to investigate ten-year seroprevalence of toxoplasmosis in patient sera submitted to Medical Microbiology Laboratory of Balıkesir University Hospital between 2015 and 2025.

Methods: The seropositivity of anti-T. gondii IgG and of anti-T. gondii IgM antibodies in patient serum samples referred to laboratory was investigated using the CMIA method, while the anti-T. gondii IgG avidity test was performed using the ELISA method. The seroprevalence of toxoplasmosis was analyzed according to patients’ age groups and gender. The study group was divided into five subgroups based on age distribution, and the data for each age group were assessed by gender.

Results: Of 10184 patients included in the study, 2033 (20.0%) were male and 8151 (80.0%) were female. Anti-T. gondii IgG seropositivity was detected in 2245 (24.0%) of 9342 patients, and anti-T. gondii IgM seropositivity was detected in 132 (1.3%) of 10184 patients. Anti-T. gondii IgG seropositivity was found to be 4.2% in male patients and 19.5% in female patients, and anti-T. gondii IgM seropositivity was found to be 0.2% in male patients and 1.1% in female patients. Avidity testing was performed on 157 patients. Low avidity values were detected in 5 (3.2%) of these patients and high avidity values were detected in 152 (96.8%).

Conclusion: Considering the clinical importance of toxoplasmosis, the potential transmission risk of Toxoplasma gondii to fetus during pregnancy (congenital toxoplasmosis) as well as to risk groups such as the immunocompromised patients and those presenting with neurological findings should be assessed with attention.