2009, Cilt 39, Sayı 3-4, Sayfa(lar) 085-088 |
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EVALUATION OF PREVALANCE EXTENDED SPECTRUM BETA-LACTAMASE PRODUCING ENTEROBACTERIACEAE MEMBERS IN FECES |
Ömer KÜÇÜKBASMACI |
İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, İstanbul |
Keywords: ESBL, Feces, Enterobacteriaceae, CTX-M |
We have studied the prevalance of extended spectrum beta lactamases (ESBL) in 150 fecal samples from 150 persons. Th ose
who were not hospitalized within last three months and were not treated by antibiotics were included in this study. Ceft azidime
and cefotaxime supplemented medium was used for the selective isolation of potential ESBL producing Enterobacteriaceae.
Colonies were screened and confirmed by the double-disc synergy test and combined disc test for ESBL production. Antimicrobial
susceptibilities of ESBL producing isolates for various antibiotics were determined. ESBL producing bacteria were
identified as Escherichia coli (84.4%), Klebsiella pneumoniae (12.5%), Klebsiella oxytoca (3.1%). Th e ESBL producing isolates
recovered from our patients corresponded to a CTX-M type (89,4%), TEM type (76.3%) and SHV type (31.5%). Information
on the prevalence and types of asymptomatic fecal flora members producing ESBL may be very helpful to improve our understanding
about the complex epidemiology of ESBLs.
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