Objective: In this study, it was aimed to determine the susceptibility to antibiotics of S. aureus isolated from patients of chronic suppurative otitis media (CSOM).

Method: The study included 100 patients who were admitted to the Otorhinolaryngology Clinic between January-2016 and June-2016 and were diagnosed as CSOM. The samples were collected from the ear of the patients by sterile swabs and steaked onto 5% defibrinated sheep blood agar. After 18-24 hours of incubation at 37°C, conventional tests were performed for the microorganisms that cultivated. The isolates were identified by both conventional methods and automated system. The antibiotic susceptibilities of these 25 isolates which identified as S. aureus, were determined in automated system.

Results: A total of 49 Staphylococcuc ssp. were isolated from specimens. These 25 isolates were identified as S. aureus. All S. aureus strains were found to be 100% susceptible to daptomycin, fusidic acid, teicoplanin, tigecycline, quinopristin-dalfopristin, trimethoprim-sulfamethoxazole, linezolite and vancomycin. The strains were found to be 96% susceptible to cefoxitin, oxacillin, fosfomycin, clindamycin and tetracycline and 92% to erythromycin, ciprofloxacin and levofloxacin. All strains were found to be 100% resistant to ampicillin and penicillin G.

Conclusion: As a result, in this study, 25% S. aureus was isolated from patients diagnosed with CSOM and susceptible to various antibiotics was determined at various rates. In order to prevent or delay the development of resistance to antibiotics, it would be more useful to start treatment according to the antibiotic susceptibility test results and to direct the treatment according to these results.