Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Telif Hakkı Devir Formu | Arşiv | Yayın Arama | Yazarlara Bilgi | Etik Politikalar | İletişim  
2022, Cilt 52, Sayı 4, Sayfa(lar) 265-273
[ Türkçe Özet ] [ PDF ] [ Benzer Makaleler ]
Investigation of the Crimean-Congo Hemorrhagic Fever Virus and the Seropositivity of Coxiella burnetii, Borrelia burgdorferi in Patients with a History of Tick Bites
Kübra Fırtına Topcu1, Zeynep Sümer2
1Dr. Yaşar Eryılmaz Doğubayazıt Devlet Hastanesi, Tıbbi Mikrobiyoloji Laboratuvarı, Ağrı, Türkiye
2Sivas Cumhuriyet Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye
Keywords: Crimean-Congo hemorrhagic fever, Lyme, Q fever, tick bite

Objective: Tick bite cases are frequently seen in our region. In our study, it was aimed to investigate the causative agents of Crimean-Congo Hemorrhagic Fever virus (CCHFV), Coxiella burnetii and Borrelia burgdorferi in patients with a history of tick bites.

Methods: Between May and September 2019, blood samples of patients admitted due to tick bites were used. The causative agents were investigated by using polymerase chain reaction for CCHFV, ELISA for C. burnetii, ELISA and Western blot for B. burgdorferi.

Results: Samples of 84 patients with a history of tick bites in their histories were used. Thirty-five-point seven percent of the cases were female and 64.3% were male. All were over the age of 18, and the occupation of 84.5% of the cases were related to farming-livestock. Thrombocytopenia was present in 84.5%. Sixty-six-pointseven percent of the cases were admitted within 7 days at the earliest after tick exposure. CCHF was positive in 76.2% of the samples and C. burnetii phase II IgM was positive in 8.3% and phase II IgG was positive in 34.5%. B. burgdorferi was IgM positive in 3.6% and IgG positive in 6% of the ELISA test. In the confirmation test, 66.7% of the B. burgdorferi ELISA IgM positive samples were positive, while all ELISA IgG positive samples were negative. C. burnetii IgM and CCHF were positive in 9.3% of the samples, C. burnetii IgG and CCHF were positive in 32.8%, B. burgdorferi IgM and CCHF were positive in 1.5% of the samples.

Conclusion: Both the seropositivities of C. burnetii and B. burgdorferi, and PCR positivity of CCHF were determined in the group of patients who were admitted with tick bites. It should be kept in mind that tick contact is a sign and transmission route not only for CCHF but also for other diseases.


[ Türkçe Özet ] [ PDF ] [ Benzer Makaleler ]
Ana Sayfa | Dergi Hakkında | Yayın Kurulu | Telif Hakkı Devir Formu | Arşiv | Yayın Arama | Yazarlara Bilgi | Etik Politikalar | İletişim