The investigated material comprised 182 Staphylococcus aureus and 273 coagulase-negative staphylococci strains isolated from various clinical specimens during the period from January 2001 to December 2001. Methicillin and fusidic acid sensitivity were determined by agar disk-diffusion method. Sixty-six (36.3 %) of Staphylococcus aureus and 108 (39.6 %) of coagulase- negative staphylococci strains were methicillin-resistant. 61 (92.4 %) of methicillin-resistant Staphylococcus aureus (MRSA) strains, 109 (94.0 %) of methicillin-sensitive Staphylococcus aureus (MSSA) strains, 91 (84.3 %) methicillin-resistant coagulase-negative staphylococci (MRCNS) strains and 147 (89.1 %) of methicillin-sensitive coagulase-negative staphylococci (MSCNS) strains were sensitive to fusidic acid.

These results indicated that fusidic acid may use as a good alternative drug for treatment of the staphylococcal infections.