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2021, Cilt 51, Sayı 1, Sayfa(lar) 061-069
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Retrospective Evaluation of Helicobacter pylori Antigen Positivity in the Stool Samples of Patients with Gastroduodenal Complaints
Tevhide Ziver Sarp1, Harika Öykü Dinç2, Doğukan Özbey3, Seher Akkuş3, Beyza Aslan3, Merve Cihan3, Nesrin Gareayaghi4, Hrisi Bahar Tokman3,Suat Sarıbaş3, Bekir Kocazeybek3
1Doğu Akdeniz Üniversitesi, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Anabilim Dalı, Gazimağusa, K.K.T.C.
2Bezmialem Vakıf Üniversitesi, Eczacılık Fakültesi, Farmasötik Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye
3İstanbul Üniversitesi, Cerrahpaşa, Cerrahpaşa Tıp Fakültesi Tıbbi Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye
4Sağlık Bilimleri Üniversitesi, İstanbul Şişli Hamidiye Etfal Eğitim Araştırma Hastanesi, Kan Merkezi, İstanbul, Türkiye
Keywords: Helicobacter pylori, prevalance, H. pylori stool antigen test

Objective: Helicobacter pylori is an important pathogen that causes the development of important gastroduodenal pathologies such as acute and chronic gastritis, ulcer and gastric cancer. This pathogen is estimated to infect about half of the world’s population. In this study, it was aimed to evaluate the five-year data retrospectively by investigating the presence of H. pylori antigen in stool samples taken from patients who applied to Istanbul University-Cerrahpaşa Medical Faculty Medical Microbiology Department Serology/ELISA laboratory with gastroduodenal complaints between January 2015 and December 2019.

Method: Stool specimens of 4696 patients admitted to the hospital with gastroduodenal complaints between January 2015 and December 2019 were analyzed using an immunochromotographic H. pylori stool antigen test containing monoclonal antibodies.

Results: Among 4696 patients who were examined retrospectively in a five-year period, 1176 (25%) had positive, and 3520 (75%) of them negative H. pylori test results. H. pylori-positivity was found in 210 (21.30%) of 986 children and 966 (26.04%) of 3710 adults. H. pylori detection rate in children was found to be significantly lower than adults (p: 0.002). H. pylori positivity was found higher in the 30-39 age range compared to other age groups.

Conclusion: Although current study results showed a lower prevalence compared to recent studies, it has been concluded that H. pylori is an important pathogen in all age groups with gastroduodenal complaints and should be monitored in the community.


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