In this study antibiotic resistances of 1257 Escherichia coli strains isolated from urinary tract infections in 1997 and 1344 in 2000 were investigated. The most resistant antibiotics against these strains in 1997 were found to be ampicillin (60.5 %), trimetoprim/ sulfometaxasol (36.3 %), ciprofloxacin (15.1 %), while no resistance were found against cefotaxime, amikacin and imipenem. Resistancy rates in 2000 were found to be ampicilline (71.4 %), trimetoprime/ sulfometaxasol (55.9 %), ciprofloxacin (29.5 %), cefotaxime (8.3 %), amikacin (6.1 %) and no resistance found to imipenem.