2009, Cilt 39, Sayı 1-2, Sayfa(lar) 022-026 |
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ANTIBIOTIC SUSCEPTIBILITY OF STAPHYLOCOCCUS AUREUS STRAINS ISOLATED FROM BLOODSTREAM INFECTIONS |
İnci TUNCER, Fatma KALEM, Mediha ÇOŞAR, Uğur ARSLAN |
Selçuk Üniversitesi Meram Tıp Fakültesi Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı, Konya |
Keywords: Staphylococcus aureus, bloodstream infection, meticillin resistance |
Abstract |
Bloodstream infections (BSI) have high morbidity and mortality rates. Staphylococcus aureus is one of the two most common
causes of BSI. Methicillin resistance has been increased in S.aureus strains. In this study, antimicrobial susceptibility
patterns of S.aureus isolated from BSI has been evaluated.
Blood cultures were performed with automated system. Th e isolates were identified as S.aureus by conventional methods
and antimicrobial susceptibility were determined by Kirby–Bauer disc diff usion method according to the criteria of Clinical
Laboratory Standarts Institute
Of the 274 S.aureus strains, 132 (48.2%) were MRSA (methicillin resistant S.aureus) and 142 (51.8%) were MSSA (methicillin
susceptible S.aureus). MRSA strains showed resistance to multiple antibiotics. Th e susceptibility rates of vancomycin,
gentamycin, erythromycin, tetracycline and ciprofl oxacin in methicillin resistant strains (MRSA) were 100%, 13%, 12%, 10%
and 9%, respectively. In the methicillin susceptible group; susceptibility rates of vancomycin, gentamycin, tetracycline ciprofloxacin
and erythromycin, were 100%, 97%, 94 %, 93 % and 91 %, respectively. Th e incidence of methicillin-resistant S.aureus
was 25.7% in 2003 and increased to 67.8% in 2006 (For 2004, 2005 and 2006 were 36.7%, 42.2% and 67.8%, respectively) but
decreased to 57.1% in 2007
In every region; antimicrobial susceptibility profile and colonisation rate of S.aureus strains should be provided for better
management of the BSI and to develop rational strategies for public health policies. |
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